A recent research study has found that in type 2 diabetes (T2D) patients, women are more likely than men to experience neuropathy symptoms. The study originally set out to determine if a vitamin D deficiency in patients with T2D increased their risk of developing neuropathic pain. Research has suggested that a vitamin D deficiency may predispose T2D patients to chronic hyperglycemia, which increases the risk for neuropathic pain. While researchers found no significant link between vitamin D and neuropathy in these T2D patients, they discovered an “association” between neuropathy and the sex of the patients.
The research results found that 76.6% of the participants with neuropathy were women, while 23.4% were male. They concluded that sex was the only significant predictor of neuropathic pain in T2D patients. The scientists did acknowledge, however, that they faced limitations in the study and that more research should be done to have more conclusive results. They stated, “The current study is the first report that did not find any association between vitamin D levels and neuropathic pain in participants.”
“Neuropathic pain is not associated with serum vitamin D but is associated with female gender in patients with type 2 diabetes mellitus,” by Mohammad Alkhatatbeh and Khalid K. Abdul-Razzak. BMJ Open Diabetes Research & Care 2019.